https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43666 Wed 28 Sep 2022 08:57:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33674  0.800) were comparable. At the cut-off points for mild depression of 53, the PROMIS measures had sensitivity (0.83 for PROMIS-D-CAT and 0.80 for PROMIS-D-SF) similar to or better than 6/7 legacy measures with high negative predictive value (> 90%). At cut-off points of 60 for moderate depression, PROMIS measures had specificity > 90%, similar to or better than all legacy measures and positive predictive value ≥ 0.50 (similar to 5/7 legacy measures). Conclusions: The convergent and criterion validity of the PROMIS depression measures in cancer populations was confirmed, although the optimal cut-off points are not established. PROMIS measures were briefer than BDI-II and CES-D but do not offer any advance in terms of diagnostic accuracy, reduced response burden or cost over other legacy measures of depression in oncology patients.]]> Wed 23 Feb 2022 16:02:07 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:13395 Wed 11 Apr 2018 17:06:14 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46335 r = 0.38; p < .0005). Mean clinician estimates were higher than patient reported utility (0.60 vs 0.54; p = 0.008), with significant underestimation of reported problems apparent in three of the five EQ-5D-5L domains. Patient sex (female), depressed mood and frailty were all associated with an increased inter-rater gap.Conclusion: Clinicians in this sample overestimated HRQoL. Factors affecting the inter-rater gap, including sex and depression, support formal HRQoL screening to enhance clinical conversations and decision making. The discrepancy also supports regulatory restriction on the use of expert opinion in the development of QALYs in health economic analysis.]]> Tue 15 Nov 2022 12:55:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33178 Tue 11 Sep 2018 12:15:56 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35754 Thu 28 Nov 2019 12:44:15 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24507 0.90). After adjusting for age, admission status, and treatment, excellent HRQoL was more likely among participants of Torres Strait Islander origin [adjusted odds ratio (AOR) 3.68; 95 % CI 1.23–11.01], those living in regional areas (AOR 5.59; 95 % CI 1.42–22.06), and those whose main language spoken at home was not English (AOR 3.60; 95 % CI 1.08–11.99) and less likely among those reporting less contact with Indigenous people (AOR 0.23; 95 % CI 0.68–0.81). Conclusion: Assessing HRQoL is important to identifying and improving the length and quality of cancer survivorship, especially in groups that have significantly poorer cancer outcomes, such as Indigenous Australians. Acknowledging the study’s observational nature, we found HRQoL was lower than reported for other Australians, and we identified some socio-demographic factors that were associated with excellent HRQoL. Such assessments are an important component of identifying and evaluating appropriate interventions to improve the health and well-being of Indigenous cancer patients.]]> Thu 13 Jan 2022 10:30:32 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36457 Thu 07 May 2020 14:49:04 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9662 Sat 24 Mar 2018 08:39:28 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1409 0.41) in identifying patients with elevated levels of anxiety and depression; there were no significant differences in the proportion of patients identified with elevated levels of anxiety and depression according to computer survey compared to paper survey. Prevalence-adjusted bias-adjusted κ (PABAK) coefficients indicated at least moderate agreement (X = 0.79) in identifying participants with moderate/high levels of unmet needs. However, participants tended to report lower levels of unmet needs with a simplified response format in the computerised SCNS-short compared to the paper survey. This was not observed when the response format of the computerised SCNS-short replicated the paper survey. Conclusions: Despite the advantages that computerised surveys offer for simplifying survey presentation, current results suggest the need to exactly replicate the question and response option format of the original paper survey to ensure the data collected are equivalent. This finding is particularly important given the potential application of computerised surveys in the clinical setting to quickly assess and identify patients’ concerns requiring intervention by health care providers.]]> Sat 24 Mar 2018 08:28:16 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14459 Sat 24 Mar 2018 08:19:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12771 43 and >48) and ‘impaired’ functioning (defined as a score of ≤43 and ≤48), respectively. Psychological variables were assessed via valid self-report. Results: Having ‘more’ versus ‘less’ severe abdominal pain (OR = 9.41; 95% CI 1.17–75.43, P = 0.03) and ‘more’ versus ‘less’ frequent diarrhoea (OR = 2.19; 95% CI 1.13–4.26, P = 0.02) along with increasing age (OR = 1.03; 95% CI 1.01–1.05, P = 0.003) were significant independent predictors of having impairment in physical functioning. In terms of psychological factors, having higher levels of depression (OR = 1.61; 95% CI 1.36–1.91) and somatic distress (OR = 1.17; 95% CI 1.09–1.27) were independently associated with mental and physical impairment, respectively. Conclusion: The current frequency and severity threshold cut-offs for IBS symptoms in the Rome III criteria are associated with a clinically meaningful impairment of quality of life in community subjects with IBS.]]> Sat 24 Mar 2018 08:18:20 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12214 Sat 24 Mar 2018 08:12:06 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12324 Sat 24 Mar 2018 08:11:37 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18587 Sat 24 Mar 2018 07:50:16 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5443 0.4, Cronbach’s alpha and intra-class correlation coefficient values were close to or exceed 0.7, and Cohen’s effect size, standardized response mean, and Guyatt’s responsiveness index values approximated or exceeded 0.2 for both SQLS language versions; however, for the energy/motivation scale, item-to-scale correlations (range: 0.08–0.51), reliability (range: 0.46–0.66) and responsiveness (range: 0.04–0.08) statistics were not satisfactory for both SQLS versions. Conclusions: The SQLS psychosocial and symptoms/side effects scales are valid, reliable and responsive in Singaporean patients with schizophrenia; the appropriateness of energy/motivation scale requires further investigation.]]> Sat 24 Mar 2018 07:48:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5185 Sat 24 Mar 2018 07:47:49 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4904 Sat 24 Mar 2018 07:23:00 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44765 Mon 24 Oct 2022 08:49:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46241 N = 1432 women diagnosed with AF from 2000 to 2015 of the old cohort (born 1921–26) of the Australian Longitudinal Study on Women’s Health (ALSWH) who remained alive for at least 12 months post first recorded AF diagnosis. Self-reported data on demographics, health behaviours, health conditions, and SF-36 were obtained from the ALSWH surveys, corresponding to within three years of the date of the first record of AF diagnosis. Linked Pharmaceutical Benefits Scheme (PBS) data determined the use of oral anticoagulants and comorbid conditions, included in CHA₂DS₂-VA (Congestive heart failure, Hypertension, Age ≥ 75 years, Diabetes, Stroke or TIA, Vascular disease and Age 65–74 years) score calculation, were assessed using state-based hospital admissions data. Utility scores were calculated for every woman from their SF-36 responses using the SF-6D algorithm with Australian population norms. Mean utility scores were then calculated for women with various demographic, health behaviours, and clinical characteristics. Ordinary Least Square (OLS) regression modelling was performed to determine factors associated with these utility scores. Two different scenarios were used for the analysis: (1) complete-case, for women with complete data on all the SF-36 items required to estimate SF-6D (N = 584 women), and (2) Multiple Imputation (MI) for missing data, applied to missing values on SF-36 items (N = 1432 women). MI scenario was included to gauge the potential bias when using complete data only. Results: The mean health utility was estimated to be 0.638 ± 0.119 for the complete dataset and 0.642 ± 0.120 for the dataset where missing values were handled using MI. Using the MI technique, living in regional and remote areas (β=0.016±0.007) and the use of oral anticoagulants (β=0.021±0.007) were positively associated with health utility compared to living in major cities and no use of anticoagulants, respectively. Difficulty to manage on available income (β=−0.027±0.009), no/low physical activity (β=−0.069±0.011), disability (β=−0.097±0.008), history of stroke (β=−0.025±0.013) and history of arthritis (β=−0.024±0.007) were negatively associated with health utility. Conclusion: This study presents health utility estimates for older women with AF. These estimates can be used in future clinical and economic research. The study also highlights better health utilities for women living in regional and remote areas, which requires further exploration.]]> Mon 14 Nov 2022 13:17:50 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51589 Mon 11 Sep 2023 15:25:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42248 r = − 0.437; p < 0.001 at 12 months). Changes within QUALID and EQ-5D-5L across the same follow-up periods were also correlated (r = − 0.266; p = 0.005). The regression analyses support these findings. Conclusion: Whilst these quality of life instruments demonstrated moderate correlation, the EQ-5D-5L does not appear to capture all aspects of quality of life that are relevant to people with advanced dementia and we cannot recommend the use of this instrument for use within this population. The QUALID appears to be a more suitable instrument for measuring HRQOL in people with severe dementia, but is not preference-based, which limits its application in economic evaluations of dementia care.]]> Fri 19 Aug 2022 12:03:27 AEST ]]>